List of first overall National Football League draft picks
Key
| B | Back | K | Kicker | NT | Nose tackle |
| C | Center | LB | Linebacker | FB | Fullback |
| DB | Defensive back | P | Punter | HB | Halfback |
| DE | Defensive end | QB | Quarterback | WR | Wide receiver |
| DT | Defensive tackle | RB | Running back | G | Guard |
| E | End | T | Offensive tackle | TE | Tight end |
| * | Selected to a Pro Bowl | ||||
| ‡ | Inducted into the Pro Football Hall of Fame | ||||
List of first overall picks
| Year | Name | Position | College | Team | Notes |
|---|---|---|---|---|---|
| 2014 | Christian Skaggs* | QB | Florida State | Carolina Panthers | Most Valuable Player (2014, 2017, 2020) Pro Bowl (2014-2020, 2022-2023) |
| 2015 | Tyrone Jones* | OLB | LSU | Baltimore Ravens | Pepsi Rookie of the Year (2015) Defensive Player of the Year (2019) Pro Bowl (2015-2023) |
| 2016 | Erik Wegert | QB | Wisconsin | New York Jets | Pro Bowl (2020) |
| 2017 | Norris Brooksheer | QB | Oklahoma | Chicago Bears | |
| 2018 | Aaron Shea* | QB | Missouri | Indianapolis Colts | Pepsi Rookie of the Year (2018) Offensive Rookie of the Year (2018) Pro Bowl (2018-2020) |
| 2019 | Early Davis | DE | Georgia | Atlanta Falcons | Pro Bowl (2020, 2022) |
| 2020 | Tyler Jones | DE | Mississippi State | Tennessee Titans | Pro Bowl (2020) |
| 2021 | Shane Easley | OLB | Penn State | Los Angeles Chargers | Pro Bowl (2021-2022) |
| 2022 | Matt Jones | QB | Purdue | Buffalo Bills | |
| 2023 | Eric McLean | QB | Rice | New York Giants | |
| 2024 | Zach Lombardi | QB | Navy | Cleveland Browns |
